Institute of Metabolism and Systems Research

 

Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis

Cell Reports [2211-1247]

Hollinshead, Kate | Munford, Haydn | Eales, Katherine | Bardella, Chiara | Li, Chunjie | Escribano Gonzalez, Cristina | Thakker, Alpesh | Nonnenmacher, Yannic | Kluckova, Katarina | Jeeves, Mark | Murren, Robert | Cuozzo, Federica | Ye, Dan | Laurenti, Giulio | Zhu, Wei | Hiller, Karsten | Hodson, David | Hua, Wei | Tomlinson, Ian | Ludwig, Christian | Mao, Ying | Tennant, Daniel

Consensus Guidance for Adult Idiopathic Intracranial Hypertension

Journal of Neurology Neurosurgery and Psychiatry [0022-3050]

Mollan, SP | Davis, B | Silver, NC | Shaw, S | Malucci, C | Wakerley, BR | Krishnan, A | Chavda, S | Ramalingam, Satheesh | Edwards, J | Hemmings, K | Williamson, M | Burdon, MA | Hassan-Smith, Zaki | Digre, K | Liu, GT | Jensen, R | Sinclair, Alexandra

The barriers to the progression of additive manufacture: perspectives from UK industry

International Journal of Production Economics [0925-5273]

Seale, Lauren | Kirkman-Brown, Jackson | Espino, Daniel | Attallah, Moataz | Shepherd, Duncan

Hepatic NADlevels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice

Molecular and Cellular Endocrinology [0303-7207]

Dall, Morten | Penke, Melanie | Sulek, Karolina | Matz-Soja, Madlen | Holst, Birgitte | Garten, Antje | Kiess, Wieland | Treebak, Jonas T

Simvastatin induces apoptosis in PTEN-haploinsufficient lipoma cells

Kassner, Franziska | Sauer, Tina | Penke, Melanie | Richter, Sandy | Landgraf, Kathrin | Korner, Antje | Kiess, Wieland | Handel, Norman | Garten, Antje

Attitudes and barriers to exercise in adults with a recent diagnosis of type 1 diabetes

BMJ open [2044-6055]

Kennedy, Amy | Narendran, Partheepan | Andrews, Robert C | Daley, Amanda | Greenfield, Sheila | ,

AP2s mutations impair calcium-sensing receptor trafficking and signaling revealing an endosomal pathway that spatially directs G-protein selectivity

Cell Reports [2211-1247]

Gorvin, Caroline M | Rogers, Angela | Hastoy, Benoit | Tarasov, Andrei I | Frost, Morten | Sposini, Silvia | Inoue, Asuka | Whyte, Michael P | Rorsman, Patrik | Hanyaloglu, Aylin C | Breitwieser, Gerda E | Thakker, Rajesh V

MR findings in brain injured survivors of monochorionic twin pregnancies complicated by single intrauterine death: a multicenter study

Radiology [0033-8419]

Conte, Giorgio | Righini, Andrea | Griffiths, Paul | Rustico, Mariangela | Lanna, Mariano | Mackie, Fiona | Pinelli, Lorenzo | Prefumo, Federico | Persico, Nicola | Igra, Mark | Parazzini, Cecilia | Doneda, Chiara | Fichera, Anna | Ambrosi, Claudia | Kilby, Mark | Triulzi, Fabio | Rossi, Andrea | Skipper, Nicholas

Cinacalcet rectifies hypercalcemia in a patient with familial hypocalciuric hypercalcemia Type 2 (FHH2) caused by a germline loss-of-function Ga11 mutation

Journal of Bone and Mineral Research [0884-0431]

Gorvin, Caroline M | Hannan, Fadil M | Cranston, Treena | Valta, Helena | Makitie, Outi | Schalin-Jantti, Camilla | Thakker, Rajesh V

Conditional and reversible activation of class A and B G protein-coupled receptors using tethered pharmacology

ACS Central Science [2374-7951]

Podewin, Tom | Ast, Julia | Broichhagen, Johannes | Fine, Nicholas | Nasteska, Daniela | Leippe, Philipp | Gailer, Manuel | Buenaventura, Teresa | Kanda, Nisha | Jones, Ben | N'Kadmi, Celine | Baneres, Jean-Louis | Marie, Jacky | Tomas, Alejandra | Trauner, Dirk | Hoffmann-Roder, Anja | Hodson, David