Prof:
Tim
Mitchell
Expression of the lux genes in Streptococcus pneumoniae modulates pilus expression and virulence

PLoS ONE [1932-6203]

Herbert, Jenny | Mitchell, Andrea | Ritchie, Ryan | Ma, Jiangtao | Ross-Hutchinson, Kirsty | Mitchell, Tim

Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge

Scientific Reports

Morozov, Giora I | Porat, Nurith | Kushnir, Tatyana | Najmuldeen, Hastyar | Adawi, Asad | Chalifa-Caspi, Vered | Benisty, Rachel | Ohayon, Ariel | Liron, Ofir | Azriel, Shalhevet | Malka, Itai | Dotan, Shahar | Portnoi, Maxim | Piotrowski, Andrew A | Kafka, Daniel | Hajaj, Barak | Fishilevich, Tali | Shagan, Marilou | Tal, Michael | Ellis, Ron | Morrison, Donald A | Mitchell, Andrea | Dagan, Ron | Yesilkaya, Hasan | Nebenzahl, Yaffa Mizrachi | Mitchell, Tim

Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA

Scientific Reports

Nerlich, Andreas | Mieth, Maren | Letsiou, Eleftheria | Fatykhova, Diana | Zscheppang, Katja | Imai-Matsushima, Aki | Meyer, Thomas F | Paasch, Lisa | Mitchell, Tim | Tönnies, Mario | Bauer, Torsten T | Schneider, Paul | Neudecker, Jens | Rückert, Jens C | Eggeling, Stephan | Schimek, Maria | Witzenrath, Martin | Suttorp, Norbert | Hippenstiel, Stefan | Hocke, Andreas C

Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation

British Journal of Pharmacology [00071188]

Hupp, Sabrina | Ribes, Sandra | Seele, Jana | Bischoff, Carolin | Förtsch, Christina | Maier, Elke | Benz, Roland | Mitchell, Tim | Nau, Roland | Iliev, Asparouh I

Streptococcus pneumoniae and lytic antibiotic therapy

Journal of Medical Microbiology [0022-2615]

Brown, Lauren April | Mitchell, Andrea | Mitchell, Tim

Pneumolysin mediates heterotypic aggregation of neutrophils and platelets in vitro

Journal of Infection [0163-4453]

Nel, Jan G. | Durandt, Chrisna | Theron, Annette J. | Tintinger, Gregory R. | Pool, Roger | Richards, Guy A. | Mitchell, Tim | Feldman, Charles | Anderson, Ronald

Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties

Microbes and Infection [1286-4579]

Lizcano, Anel | Akula Suresh Babu, Ramya | Shenoy, Anukul T | Saville, Alison Maren | Kumar, Nikhil | D'Mello, Adonis | Hinojosa, Cecilia A | Gilley, Ryan P | Segovia, Jesus | Mitchell, Tim | Tettelin, Hervé | Orihuela, Carlos J

Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes

Toxins [2072-6651]

Maurer, Jana | Hupp, Sabrina | Bischoff, Carolin | Foertsch, Christina | Mitchell, Tim | Chakraborty, Trinad | Iliev, Asparouh I

Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack

Biochimica et Biophysica Acta (BBA) - General Subjects [03044165]

Wolfmeier, Heidi | Radecke, Julika | Schoenauer, Roman | Koeffel, René | Babiychuk, Viktoria S. | Drücker, Patrick | Hathaway, Lucy J. | Mitchell, Tim | Zuber, Benoît | Draeger, Annette | Babiychuk, Eduard B.

NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence

Scientific Reports

Kostadinova, Elena | Chaput, Catherine | Gutbier, Birgitt | Lippmann, Juliane | Sander, Leif E | Mitchell, Tim | Suttorp, Norbert | Witzenrath, Martin | Opitz, Bastian