Prof:
David
Hodson
Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis

Cell Reports [2211-1247]

Hollinshead, Kate | Munford, Haydn | Eales, Katherine | Bardella, Chiara | Li, Chunjie | Escribano Gonzalez, Cristina | Thakker, Alpesh | Nonnenmacher, Yannic | Kluckova, Katarina | Jeeves, Mark | Murren, Robert | Cuozzo, Federica | Ye, Dan | Laurenti, Giulio | Zhu, Wei | Hiller, Karsten | Hodson, David | Hua, Wei | Tomlinson, Ian | Ludwig, Christian | Mao, Ying | Tennant, Daniel

Conditional and reversible activation of class A and B G protein-coupled receptors using tethered pharmacology

ACS Central Science [2374-7951]

Podewin, Tom | Ast, Julia | Broichhagen, Johannes | Fine, Nicholas | Nasteska, Daniela | Leippe, Philipp | Gailer, Manuel | Buenaventura, Teresa | Kanda, Nisha | Jones, Ben | N'Kadmi, Celine | Baneres, Jean-Louis | Marie, Jacky | Tomas, Alejandra | Trauner, Dirk | Hoffmann-Roder, Anja | Hodson, David

New understanding of beta cell heterogeneity and in-situ islet function

Diabetes [0012-1797]

Benninger, Richard | Hodson, David

Glucocorticoids reprogram beta cell signaling to preserve insulin secretion

Diabetes [0012-1797]

Fine, Nicholas | Doig, Craig | Elhassan, Yasir | Vierra, Nicholas | Marchetti, Piero | Bugliani, Marco | Nano, Rita | Piemonti, Lorenzo | Rutter, Guy | Jacobson, David A | Lavery, Gareth | Hodson, David

Local and regional control of calcium dynamics in the pancreatic islet

Diabetes, Obesity and Metabolism [1462-8902]

Rutter, Guy | Hodson, David | Chabosseau, Pauline | Pullen, Timothy J | Leclerc, Isabelle

Optical control of GPR40 signalling in pancreatic ß-cells

Chemical Science [2041-6520]

Frank, James | Yushchenko, Dmytro | Fine, Nicholas | Duca, Margherita | Citir, Mevlut | Broichhagen, Johannes | Hodson, David | Schulz, Carsten | Trauner, Dirk

A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus

Science Translational Medicine [1946-6234]

Botfield, Hannah | Uldall, Maria S | Westgate, Connar | Mitchell, James | Hagen, Snorre M | Gonzalez, Ana | Hodson, David | Jensen, Rigmor H | Sinclair, Alexandra

Potent prearranged positive allosteric modulators of the glucagon-like peptide 1 receptor

Open Chemistry [2391-5420]

Jones, Ben J. | Scopelliti, Rosario | Tomas, Alejandra | Hodson, David | Broichhagen, Johannes

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

Chemical Science [2041-6520]

Podewin, Tom | Broichhagen, Johannes | Frost, Christina | Groneberg, Dieter | Ast, Julia | Meyer-Berg, Helena | Fine, Nicholas | Friebe, Andreas | Zacharias, Martin | Hodson, David | Trauner, Dirk | Hoffmann-Röder, Anja

RAMP2 influences glucagon receptor pharmacology via trafficking and signaling

Endocrinology [1758-3918]

Cegla, Jaimini | Gardiner, James V. | Hodson, David | Marjot, Thomas | McGlone, Emma R. | Tan, Tricia M. | Bloom, Stephen R.